I’m BSc (Biomedical Sciences, University of Mogi das Cruzes, Sao Paulo), MA and PhD (Molecular Biology, Federal University of Sao Paulo). During my PhD, I had an internship at W. Hasselbach’s lab (Max Planck Institute for Medical Research, Heidelberg, D), where we demonstrated for the first time that T4 administration increased SERCA expression and activity in rabbit muscles. My post-doc was at Dr. Chopra’s laboratory, Division of Endocrinology, UCLA. Since 1983, I have been a Professor and Researcher at the Department of Physiology and Biophysics, University of Sao Paulo; now I’m Full Professor and Head of the Department. We have published papers across a wide spectrum of thyroid hormone (TH) actions/synthesis. We were the first to show that T3 posttranscriptionally regulates GH, TSHa&b and proinsulin mRNAs’ stability and translation rate. We have identified some molecular events involved on the effect of excess iodine on the Wolff-Chaikoff effect and escape. We have investigated and published papers on the interplay between TH and insulin actions and recently our focus is the contribution of TH as an adjuvant agent in the experimental diabetes mellitus treatment. I’m member of important Brazilian Scientific Societies, LATS (Executive Committee), Endocrine Society and European Society of Endocrinology, and of the advisory and scientific committee of the ERGO project, about Thyroid Disruptors, at European Commission (Horizon 2020). We have attended national/international meetings and got some awards. The Brazilian Council for the Development of Science and Technology (CNPq) and the Support Foundation for Research of Sao Paulo State (FAPESP) support our studies.
The lecture video：0
Symposium 9 Thyroid Hormone Action in Metabolism
|Speaker||Regulation of Insulin Action|