Dr. Yun-Bo Shi is a senior investigator and section head at NICHD, NIH, USA. Dr. Shi received his BS degree from Wuhan University, China and his PhD degree from University of California, Berkeley, USA. After postdoctoral training at Carnegie Institution, USA, Dr. Shi established his own research group in NICHD, NIH, in 1992. Dr. Shi’s laboratory has been studying the molecular basis of thyroid hormone regulation of vertebrate development by using Xenopus metamorphosis as a model. Dr. Shi has published over 230 articles, including more than 160 research papers, edited three books and written a monograph on amphibian metamorphosis. For his accomplishments, Dr. Shi has received many awards and recognitions, including the 2009 NIH APAO (Asian & Pacific Islander American Organization) Award for outstanding accomplishments in biomedical research and the 2008 Van Meter Award by the American Thyroid Association. In 2012, Dr. Shi was elected as a Fellow of the American Association for the Advancement of Science. Dr. Shi was an editor of Cell Research from 1997 to 2010 and the Editor-in-Chief of Cell and Bioscience from 2010 to 2020, and has served as a board member of several journals including Thyroid. Finally, Dr. Shi has been elected to serve as an official or council member of several scientific organizations, including North American Society for Comparative Endocrinology, where Dr. Shi is the current NASCE’s Vice-President/President-Elect.