Dr. Yen currently is Professor at Duke-NUS Graduate Medical School in Singapore and Head of the Laboratory of Hormonal Regulation in the Cardiovascular and Metabolic Disorders Program.  He also is Professor of Medicine at Duke University School of Medicine, Durham, NC and a member of the Duke Molecular Physiology Institute. He obtained his M.D. from Johns Hopkins, completed residency in internal medicine at University of Chicago, and fellowship training in endocrinology at NIH.  He was formerly Assistant Professor at Harvard Medical School, Chief of the Neuro-endocrinology and Molecular Regulation Section of the Clinical Endocrinology Branch at NIDDK (National Institutes of Health, Bethesda, MD), and Associate Professor of Medicine and Pharmacology at Johns Hopkins University School of Medicine.  He has served on the editorial boards of Endocrinology, Molecular Endocrinology, and Thyroid.  He is a previous recipient of the Boot Thyroid Mentor Award from the Endocrine Society and the 2020 Nagataki-Fujifilm Prize from the Asia-Oceanic Thyroid Association (AOTA). He also is a U.S. board-certified physician in internal medicine as well as endocrinology and metabolism. He is an AOTA Council Member, the AOTA delegate to the World Thyroid Foundation, and the Singapore Representative to the International Iodine Global Network.  He also has served as College Master of Sheares College, Duke-NUS Medical School since 2010.   His research interests include endocrine regulation of transcription, autophagy, and lipid metabolism in normal and disease states such as non-alcoholic fatty liver disease, GSD1a, diabetes and obesity.